Interplay of Genes and Environment across Multiple Studies
Studies
0
The maing objective of the IGEMS is to understand why early life adversity, and social factors such as isolation and loneliness, are associated with diverse outcomes including mortality, physical functioning (health, functional ability), and psychological functioning (well-being, cognition), particularly in later life.
Visit IGEMS
Members
| Investigators | Contacts |
|---|---|
|
General Information
- Year created
- 2012
- Types of cohorts
-
- Population cohort
- Countries
-
- Sweden
- Denmark
- Finland
- United States of America
- Australia
- Setting
- International
- Funding
- National Institutes of Health Grants No. R01 AG037985, R56 AG037985, RF1 AG058068, R01 AG059329 and R01 AG060470.
- Criteria of cohort's to be included
- Cohorts involving twins with measures of physical health, cognitive health and emotional health, and measures of multiple facets of adult socioeconomic status (SES; e.g.occupation, education, financial strain)
- Socio-environmental context
-
- Environmental hazards
- Work-related stress
Participants
Number of participants
- Total
- 76,233
- With harmonized data
- 76,233
Age range of the samples
- Minimum age
- 14
- Maximum age
- 103
Methodology for harmonization and integration
- Strategy of harmonization
- Ex-post
- Data processing methods
-
- Algorithmic
- Calibration
- Standardisation
- Latent variable model
- Type of infrastructure
- Some centrally, other locally
- Integrative data analysis
-
- Meta-analyses
- Pooled analyses
- Software
-
- R / Rmarkdown
- Stata
- SAS
- Other
- Supplementary information
- Harmonization has been done for specific analyses. Some research papers: - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833715/ - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706656/
Number of cohorts
- Total
- 18
- With harmonized data
- 18
- Will more cohorts be harmonized?
- Number of harmonized variables (max.)
- 31
Access
- Availability of metadata
- Under request
- Availability of individual data