Initiative / ICC-dementia

International Centenarian Consortium - dementia

International Centenarian Consortium - dementia

ICC-dementia logo
Studies 17
The aim of ICC-dementia is to harmonise centenarian and near-centenarian studies internationally to describe the cognitive and functional profiles of exceptionally old individuals, and ascertain the trajectories of decline and thereby the age-standardised prevalence and incidence of dementia. The consortium is also interested in the genetic and environmental determinants of dementia-free exceptional longevity.
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Investigators Contacts
  • Dr. Prof. Perminder Sachdev
    Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney

General Information

Year created
Types of cohorts
  • Population cohort
America, Asia, Europe and Oceania
Philanthropic funding to the Centre for Healthy Brain Ageing
Criteria of cohort's to be included
Studies are eligible to participate in ICC-Dementia if they meet the following criteria: 1. The main focus is on individuals aged ≥95 years 2. Have a minimum sample of 80 individuals 3. Assessment includes measures of cognitive function and activities of daily living 4. Informed consent forms allow for de-identified data sharing with academic partners. All participating studies have the opportunity to participate in the analyses and to propose specific projects and papers.
Health topic
  • Ageing
  • Mental health
  • Neurological diseases
Socio-environmental context
  • NA


Number of participants


Age range of the samples

Minimum age

Methodology for harmonization and integration

Strategy of harmonization
Data processing methods
  • NA
  • Type of infrastructure
    Some centrally, other locally
    Integrative data analysis
    • Pooled analyses
  • NA
  • Supplementary information
    Initial attempts at harmonising key variables are in progress. More information: Brodaty H et al. ICC-dementia (International Centenarian Consortium - dementia): an international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups. BMC Neurology (2016) 16:52 DOI 10.1186/s12883-016-0569-4

    Number of cohorts

    With harmonized data
    Will more cohorts be harmonized?


    Availability of metadata
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    100+ The 100-plus Study Population cohort 500
    90 + 90+ Study Population cohort 1,600
    CaT Centenarians at Trieste (CaT) Population cohort 70
    DH100-II 2nd Heidelberg Centenarian Study (HD100-II) Population cohort
    FH Fordham Centenarian Study (FH) Population cohort 119
    GCS Georgia Centenarian Study (GCS) Population cohort 244
    Go95+ Gothenburg Centenarian Study (Go95+) Population cohort 80
    HKCS Hong Kong Centenarian Study (HKCS) Population cohort 153
    LGP Longevity Gene Project (LGP) Population cohort 500
    M80+ Monzino 80+ Study (M80+) Population cohort 2,139
    CFAS Cognitive Function and Ageing Study (CFAS) Population cohort 13,004
    OBAS Oregon Brain Aging Study (OBAS) Population cohort 156
    PCS Polish Centenarian Study (PCS) Population cohort 86
    PT100 Oporto Centenarian Study (PT100) Population cohort 140
    SCS Sydney Centenarian Study Population cohort 300
    SwCS Swedish Centenarian Study (SwCS) Population cohort 164
    TCS Tokyo Centenarian Study Population cohort 514