International Childhood Cancer Cohort Consortium
Studies
6
The aim of I4C is to understand the aetiology and mechanistic underpinnings of childhood cancer by exploiting prospectively collected exposure and biomarker data.
A summary is provided in the publication - 'The International Childhood Cancer Cohort Consortium (I4C): A research platform of prospective cohorts for studying the aetiology of childhood cancers' at the following link - https://onlinelibrary.wiley.com/doi/full/10.1111/ppe.12519
Visit I4C
Investigators | Contacts |
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General Information
- Year created
- 2004
- Types of cohorts
-
- Population cohort
- Countries
-
- Australia
- Denmark
- Brazil
- China
- France
- Italy
- Israel
- Japan
- Norway
- United Kingdom
- United States of America
- Setting
- International
- Funding
- NA
- Criteria of cohort's to be included
- Cohorts eligible for inclusion in the I4C need to recruit mothers during pregnancy or around delivery. Eligible cohorts must systematically ascertain cases of CC in the offspring and should include questionnaire and/or other exposure data that address key CC aetiology-related hypotheses. The specific goals and original outcomes of the individual cohorts (eg, pregnancy complications and/ or serious chronic childhood conditions) may vary, but critical data items include parental and offspring demographic, life style, medical, reproductive, environmental factors and parental occupational information. Specific responsibilities of newly joining or participating I4C cohorts include sharing of data (and biospecimens-if available) for current and future proposals.
- Health topic
-
- Birth, infancy and childhood health
- Cancer
- Socio-environmental context
-
- NA
Participants
Number of participants
- Total
- 388,120
Age range of the samples
- Minimum age
- 0
- Maximum age
- 30
Methodology for harmonization and integration
- Strategy of harmonization
- Ex-post
- Data processing methods
-
- NA
- Type of infrastructure
- Some centrally, other locally
- Integrative data analysis
-
- Pooled analyses
- Software
-
- NA
- Supplementary information
- https://www.mcri.edu.au/research/projects/international-childhood-cancer-cohortconsortium-i4c
Number of cohorts
- Total
- 6
- With harmonized data
- 6
- Will more cohorts be harmonized?
- Number of harmonized variables (max.)
- 20
Access
- Availability of metadata
- Availability of individual data
Individual Studies
Acronym | Name | Study design | Participants | Countries |
---|---|---|---|---|
ALSPAC | Avon Longitudinal Study of Parents and Children | Population cohort | 14,541 | United Kingdom |
CPP | Collaborative Perinatal Project | Population cohort | 50,000 | |
DNBC | Danish National Birth Cohort | Population cohort | 101,042 | |
JPS | Jerusalem Perinatal Study (JPS) | Population cohort | 92,408 | |
MoBa | Norwegian Mother and Child Cohort Study | Population cohort | 285,200 | |
TAHS | Tasmanian Infant Health Study (TAHS) | Population cohort | 7,380 |