Initiative / I3C

International Childhood Cardiovascular Cohort Consortium

International Childhood Cardiovascular Cohort Consortium

I3C logo
Studies 7
The objectives of I3C are: 1. Identify incident cardiovascular endpoints using self-reported morbidity validated by adjudication of medical records, and 2. Identify decedents using the National Death Index and adjudicate cause of death for deceased participants.
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Investigators Contacts
  • Prof. Terry Dwyer

General Information

Year created
2009
Types of cohorts
  • Population cohort
Countries
  • United States of America
  • Finland
  • Australia
Setting
International
Funding
This project has received funding from the National Institutes of Health (grant number RO1HL121230).
Criteria of cohort's to be included
long-term observational studies of risk factors for heart disease started in groups of school children.
Socio-environmental context
  • NA

Participants

Number of participants

Total
42,189
With harmonized data
31,000

Age range of the samples

Minimum age
3
Maximum age
19

Methodology for harmonization and integration

Strategy of harmonization
Ex-post
Data processing methods
  • NA
  • Type of infrastructure
    Some centrally, other locally
    Integrative data analysis
    • Meta-analyses
    • Pooled analyses
    Software
  • NA
  • Supplementary information
    Harmonisation has been done for specific analyses. More information: https://dx.doi.org/10.1016%2Fj.cct.2018.04.009

    Number of cohorts

    Total
    7
    With harmonized data
    7
    Will more cohorts be harmonized?
    Number of harmonized variables (max.)
    15

    Access

    Availability of metadata
    Under request
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    BHS Bogalusa Heart Study Population cohort 12,164
    CDAH Childhood Determinants of Adult Health Study Population cohort 8,498
    LRC Princeton Lipid Research Study 6,775
    MPLS Minneapolis Childhood Cohort Studies Population cohort 1,574
    Muscatine Muscatine Study Population cohort 11,377
    NGHS The National Heart, Lung, and Blood Institute (NHLBI) Growth and Health Study Population cohort 2,379
    YFS Cardiovascular Risk in Young Finns Study Population cohort 3,596