Initiative / HALCyon

Year created

2008

Types of cohorts

• Population cohort

Countries

• United Kingdom

Setting

National

Funding

This project received funding from the New Dynamics of Ageing, coordinated by the UKRI Economic and Social Research Council - ESRC (2008-2014) (RES-353-25-0001)

Criteria of cohort's to be included

The project focus on studies based in the UK with life course data and specific ageing outcomes measured in midlife or old age and/or repeat measures of capability in later life

Health topic

• Ageing

Socio-environmental context

• NA

Number of participants

Total

40,000

Age range of the samples

Minimum age

50

Maximum age

90

Strategy of harmonization

Ex-post

Data processing methods

NA

Type of infrastructure

Some centrally, other locally

Integrative data analysis

• Meta-analyses
• Pooled analyses

Software

Stata

Supplementary information

Examples of outputs from this collaborative project: Alfred T, Ben-Shlomo Y, Cooper R, Hardy R, Cooper C, Deary IJ, Elliott J, Gunnell D, Harris SE, Kivimaki M, Kumari M, Martin RM, Power C, Sayer AA, Starr JM, Kuh D, Day IN; HALCyon Study Team. Associations between APOE and low-density lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme. Age (Dordr). 2014;36(4):9673. doi: 10.1007/s11357-014-9673-9. Epub 2014 Jul 30. Birnie K, Cooper R, Martin RM, Kuh D, Aihie Sayer A, Alvarado BE, Bayer A, Christensen K, Cho S, Cooper C, Corley J, Craig L, Deary IJ, Demakakos P, Ebrahim S, Gallacher J, Gow AJ, Gunnell D, Haas S, Hemmingsson T, Inskip H, Jang S, Noronha K, Osler M, Palloni A, Rasmussen F, Santos-Eggimann B, Spagnoli J, Starr J, Steptoe A, Syddall H, Tynelius P, Weir D, Whalley LJ, Zunzunegui MV, Ben-Shlomo Y, Hardy R on behalf of the HALCyon study team. Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis. PLoS ONE 2011; 6(1):e15564. Cooper R et al. Age and Gender Differences in Physical Capability Levels from Mid-Life Onwards: The Harmonisation and Meta-Analysis of Data from Eight UK Cohort Studies. PlosOne, 2011, Volume 6, Issue 11, e27899 Cooper R, Stafford M, Hardy R, Aihie Sayer A, Ben-Shlomo Y, Cooper C, Craig L, Deary IJ, Gallacher J, McNeill G, Starr JM, Kuh D and Gale CR on behalf of the HALCyon study team Physical capability and subsequent positive mental wellbeing in older people: findings from five HALCyon cohorts. AGE 2014;36:445-456 Gardner MP, Martin-Ruiz C, Cooper R, Hardy R, Sayer AA, Cooper C, Deary IJ, Gallacher J, Harris SE, Shiels PG, Starr JM, Kuh D, von Zglinicki T, Ben-Shlomo Y and the HALCyon study team. Telomere length and physical performance at older ages:an individual participant meta-analysis. PLoS One 2013 8(7): e69526 Hardy R, Cooper R, Aihie Sayer A, Ben-Shlomo Y, Cooper C, Deary IJ, Demakakos P, Gallacher J, Martin RM, McNeill G, Starr JM, Steptoe A, Syddall H, Kuh D on behalf of the HALCyon study team. Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme. PLoS One 2013;8(2):e56483

Number of cohorts

Total

9

With harmonized data

9

Will more cohorts be harmonized?

Access

Availability of metadata

Availability of individual data