Biobank Standardisation and Harmonisation for Research Excellence in the European Union
Studies
13
The objective of BioSHaRE-EU is to build upon tools and methods available to achieve solutions for researchers to use pooled data from different cohort and biobank studies. This, in order to obtain the very large sample sizes needed to investigate current questions in multifactorial diseases
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| Investigators | Contacts |
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General Information
- Year created
- 2010
- Types of cohorts
-
- Population cohort
- Countries
-
- Canada
- Germany
- Italy
- Ireland
- United Kingdom
- Finland
- Netherlands
- Norway
- Setting
- International
- Funding
- European Union
- Criteria of cohort's to be included
- Large biobanks or study cohorts with no specific health context.
- Health topic
-
- Environmental health
- Chronic diseases
- Socio-environmental context
-
- Air pollution
- Urbanization
Participants
Number of participants
- Total
- 935,227
Age range of the samples
- Minimum age
- 18
Methodology for harmonization and integration
- Strategy of harmonization
- Ex-post
- Data processing methods
-
- NA
- Type of infrastructure
- Data are in different locations
- Integrative data analysis
-
- Pooled analyses
- Federated analyses
- Software
-
- OBiBa (Opal/Mica)
- DataSHIELD
- R / Rmarkdown
- Supplementary information
- A variety of tools and methods are developed in BioSHaRE for retrospective and prospective harmonisation: https://cordis.europa.eu/docs/results/261/261433/final1-final-publishable-summary---update-jan.pdf More information: https://dx.doi.org/10.1089%2Fbio.2015.0124
Number of cohorts
- Total
- 15
- With harmonized data
- 8
- Will more cohorts be harmonized?
- Number of harmonized variables (max.)
- 100
Access
- Availability of metadata
- Availability of individual data
Individual Studies
| Acronym | Name | Study design | Participants | Countries |
|---|---|---|---|---|
| CaG | CARTaGENE | Population cohort | 43,000 | |
| CHRIS | Cooperative Health Research in South Tyrol Study (Italy) | Population cohort | 13,393 | |
| EPIC-Oxford | European Prospective Investigation into Cancer | Population cohort | 65,000 | |
| FINRISK | The National FINRISK Study- North Karelia Project | Population cohort | 35,000 | |
| HUNT | The HUNT Study | Population cohort | 123,000 | Norway |
| KORA | Cooperative health research in the Region of Augsburg | Population cohort | 18,000 | |
| LifeLines | LifeLines Cohort Study & Biobank | Population cohort | 167,000 | |
| MICROS | Microisolates in South Tyrol Study | Population cohort | 1,175 | |
| Mitchelstown cohort | Cork and Kerry Diabetes and Heart Disease Study Phase II - Mitchelstown cohort | Patients' cohort | 2,047 | |
| NCDS | National Child Development Study | Population cohort | 17,634 | |
| PREVEND | Prevention of REnal and Vascular ENd-stage Disease | Population cohort | 8,592 | |
| SHIP | Study of Health in Pomerania | Population cohort | 7,008 | |
| UK Biobank | UK Biobank | Population cohort | 502,543 |