Initiative / BioSHaRE-EU

Biobank Standardisation and Harmonisation for Research Excellence in the European Union

Biobank Standardisation and Harmonisation for Research Excellence in the European Union

BioSHaRE-EU logo
Studies 13
The objective of BioSHaRE-EU is to build upon tools and methods available to achieve solutions for researchers to use pooled data from different cohort and biobank studies. This, in order to obtain the very large sample sizes needed to investigate current questions in multifactorial diseases
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Investigators Contacts
  • Rita Wissa
    Research Institute of the McGill University Health Centre (RI-MUHC)
  • Dr. Isabel Fortier
    Research Institute of the McGill University Health Centre

General Information

Year created
Types of cohorts
  • Population cohort
  • Canada
  • Germany
  • Italy
  • Ireland
  • United Kingdom
  • Finland
  • Netherlands
  • Norway
European Union
Criteria of cohort's to be included
Large biobanks or study cohorts with no specific health context.
Health topic
  • Environmental health
  • Chronic diseases
Socio-environmental context
  • Air pollution
  • Urbanization


Number of participants


Age range of the samples

Minimum age

Methodology for harmonization and integration

Strategy of harmonization
Data processing methods
  • NA
  • Type of infrastructure
    Data are in different locations
    Integrative data analysis
    • Pooled analyses
    • Federated analyses
  • OBiBa (Opal/Mica)
  • DataSHIELD
  • R / Rmarkdown
  • Supplementary information
    A variety of tools and methods are developed in BioSHaRE for retrospective and prospective harmonisation: More information:

    Number of cohorts

    With harmonized data
    Will more cohorts be harmonized?
    Number of harmonized variables (max.)


    Availability of metadata
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    CaG CARTaGENE Population cohort 43,000
    CHRIS Cooperative Health Research in South Tyrol Study (Italy) Population cohort 13,393
    EPIC-Oxford European Prospective Investigation into Cancer Population cohort 65,000
    FINRISK The National FINRISK Study- North Karelia Project Population cohort 35,000
    HUNT The HUNT Study Population cohort 123,000 Norway
    KORA Cooperative health research in the Region of Augsburg Population cohort 18,000
    LifeLines LifeLines Cohort Study & Biobank Population cohort 167,000
    MICROS Microisolates in South Tyrol Study Population cohort 1,175
    Mitchelstown cohort Cork and Kerry Diabetes and Heart Disease Study Phase II - Mitchelstown cohort Patients' cohort 2,047
    NCDS National Child Development Study Population cohort 17,634
    PREVEND Prevention of REnal and Vascular ENd-stage Disease Population cohort 8,592
    SHIP Study of Health in Pomerania Population cohort 7,008
    UK Biobank UK Biobank Population cohort 502,543