Initiative / BBMRI-NL



Studies 22
The projects mission is to maximize the use of biosamples, images and data for health research on the prevention, diagnosis and treatment of diseases. For this, these resources are available in a FAIR way: Findable, Accessible, Interoperable and Reusable. This is done in compliance with ethical, legal and privacy demands, and with active participation of donors, citizens and patients.
Investigators Contacts
  • Gerrit Meijer
    European research infrastructure for biobanking
  • Cisca Wijmenga
    European research infrastructure for biobanking

General Information

Year created
Types of cohorts
  • Population cohort
  • Netherlands
This project has received funding from the NWO, Netherlands Organization for Scientific Research and from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 676550.
Criteria of cohort's to be included
Cohorts with Genetic, epigenetic, transcriptome and metabolome data available.
Health topic
  • Biomedicine
  • Genetics
  • Other -omics
  • Medical imaging
Socio-environmental context
  • NA


Number of participants

With harmonized data

Age range of the samples

Minimum age
Maximum age

Methodology for harmonization and integration

Strategy of harmonization
Data processing methods
  • NA
  • Type of infrastructure
    Data are in different locations
    Integrative data analysis
    • NA
  • Molgenis
  • Number of cohorts

    Will more cohorts be harmonized?


    Availability of metadata
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    ALPHAOMEGA The Alpha Omega Cohort Clinical trial cohort 4,837
    BIOMarCS BIOMarker study to identify the Acute risk of a Coronary Syndrome Patients' cohort 844
    CHARM Child Health Advances from Research with Mothers Population cohort 2,000
    CHECK Cohort Hip and Cohort Knee Patients' cohort 1,002
    CODAM Cohort on Diabetes and Atherosclerosis Maastricht Population cohort 574
    DZS_WF Diabetes Zorgsysteem West-Friesland Patients' cohort 12,673
    FUNCTGENOMICS - HFGP Human Functional Genomics Project (HFGP) Population cohort 5,300
    GARP Genetics of ARthritis en Progression Patients' cohort 600
    HELIUS Healthy Life in an Urban Setting Population cohort 24,789
    LifeLines LifeLines Cohort Study & Biobank Population cohort 167,000
    LLS (LLS_PARTOFFS) Leiden Longevity Study (Offspring and their partners) Case-control 2,465
    NESDA Netherlands Study of Depression and Anxiety Case-control 3,348
    RAAK Research Arthritis and Articular Cartilage Patients' cohort 33
    STEMI GIPS-III Glycometabolic Intervention as adjunct to Primary percutaneous intervention in ST elevation myocardial infarction Clinical trial cohort 380
    TOMaaT Transfusie Op Maat (Patient Blood Management ) Clinical trial cohort 683
    UCORBIO Utrecht Coronary Biobank Patients' cohort 2,589
    LLS_SIBS Leiden Longevity Study (Nonagenarians) Population cohort 991
    RS Rotterdam Study Population cohort 14,926
    ERF Erasmus Rucphen Family study Population cohort 2,065
    VUNTR Netherlands Twin Registry Population cohort 60,000
    POSPER Prospective Study of Pravastatin in the Elderly at Risk Patients' cohort 649
    TACTICS Transfusion induced complications ; transfusion associated complications study. Patients' cohort 1,548