Initiative / ATHLOS

Ageing Trajectories of Health: Longitudinal Opportunities and Synergies

Ageing Trajectories of Health: Longitudinal Opportunities and Synergies

Studies 18

The objective of the ATHLOS Project is to achieve a better understanding of ageing by identifying patterns of healthy ageing pathways or trajectories, the determinants of those patterns, the critical points in time when changes in trajectories are produced, and to propose timely clinical and public health interventions to optimize healthy ageing. Moreover, a new definition of 'old age' based on many characteristics rather than just the classical chronological definition of age will be used for calculating projections in each specific population and guide policy recommendations. To do so, the Consortium will create a harmonised dataset with over 400,000 individuals collated from existing longitudinal studies of ageing and including information on physical and mental health, biomarkers, life style habits, social environment and participation, among others.

ATHLOS is a five-year project funded by the European Union's Horizon 2020 Research and Innovation Programme under grant agreement number 635316.

The Consortium is coordinated by Dr Josep Maria Haro (Parc Sanitari Sant Joan de Déu) and consists of 14 partners from 11 European countries.

Investigators Contacts
  • Dr Josep Maria Haro
    Parc Sanitari Sant Joan de Déu
  • Dr Josep Maria Haro
    Parc Sanitari Sant Joan de Déu

General Information

Year created
Types of cohorts
  • Population cohort
  • Cuba
  • Mexico
  • Dominican Republic
  • Puerto Rico
  • China
  • Peru
  • India
  • Venezuela
  • Austria
  • Australia
  • Greece
  • Spain
  • Finland
  • Poland
  • United Kingdom
  • Russian
  • Lithuania
  • Czech Republic
  • United States of America
  • Japan
  • Ghana
  • Netherlands
  • South Korea
  • South Africa
  • Denmark
  • Hungary
  • Sweden
  • Switzerland
  • Ireland
  • Estonia
  • Belgium
  • Israel
  • Slovenia
  • Croatia
  • Luxembourg
  • Portugal
  • France
  • Germany
  • Italy
European Union’s Horizon 2020 research and innovation programme
Criteria of cohort's to be included
Each study includes one or more populations and provides data on health determinants and age-related events.
Health topic
  • Ageing
  • General epidemiology


Number of participants

With harmonized data

Age range of the samples

Minimum age
Maximum age

Methodology for harmonization and integration

Strategy of harmonization
Data processing methods
  • Algorithmic
  • Calibration
  • Standardisation
  • Latent variable model
  • Type of infrastructure
    Some centrally, other locally
    Integrative data analysis
    • Pooled analyses
  • OBiBa (Opal/Mica)
  • R / Rmarkdown
  • Supplementary information
    A platform of free software applications, developed by Maelstrom Research, is used to store the original datasets, guide the harmonization process and create a web portal for the studies from the ATHLOS Consortium, as well as the final harmonized databases. The UBCoS study is the only study that harmonized data is kept in their institution. The website with the repository of the ATHLOS harmonized datasets: Github address with the Rmarkdown codes of harmonization:

    Number of cohorts

    With harmonized data
    Will more cohorts be harmonized?
    Number of harmonized variables (max.)


    Availability of metadata
    Availability of individual data
    Under request

    Individual Studies

    Acronym Name Study design Participants Countries
    10/66 The 10/66 Dementia Research Group Population-Based Cohort Study Population cohort 15,901 Cuba , India , China , Peru , Mexico , Puerto Rico , Dominican Republic , Venezuela
    ALSA Australian Longitudinal Study of Aging Population cohort 2,087 Australia
    ATTICA The ATTICA Study Population cohort 3,042 Greece
    CHARLS The China Health and Retirement Longitudinal Study Population cohort 17,708 China
    COURAGE Collaborative Research on Ageing in Europe Population cohort 10,800 Finland , Poland , Spain
    ELSA English Longitudinal Study of Ageing Population cohort 12,099 United Kingdom
    ENRICA Seniors-ENRICA Population cohort 2,614 Spain
    H2000/11 Health 2000/2011 Population cohort 22,261 Finland
    HAPIEE The Health, Alcohol and Psychosocial factors in Eastern Europe Study Population cohort 36,106 Czech Republic , Poland , Russian , Lithuania
    HRS Health and Retirement Survey Population cohort 37,317 United States of America
    JSTAR Japanese Study of Aging and Retirement Population cohort 7,268 Japan
    KLOSA The Korean Longitudinal Study of Ageing Population cohort 10,254 South Korea
    LASI The Longitudinal Aging Study in India Population cohort 1,683 India
    MHAS The Mexican Health and Aging Study Population cohort 15,146 Mexico
    SAGE WHO Study on Global Ageing and Adult Health Population cohort 63,437 South Africa , Ghana , China , India , Russian , Mexico
    SHARE The Survey of Health, Ageing and Retirement in Europe Population cohort 30,811 Austria , Belgium , Czech Republic , Denmark , Estonia , France , Greece , Hungary , Ireland , Israel , Italy , Netherlands , Poland , Sweden , Switzerland , Germany , Luxembourg , Croatia
    TILDA The Irish Longitudinal Study of Ageing Population cohort 8,500
    UBCoS The Uppsala Birth Cohort Multigenerational Study Other 61,613 Sweden